MXCuBE-ISPyB Joint Meeting, DLS, UK (17 - 19 November 2025)

17 Nov 2025, 08:30 → 19 Nov 2025, 18:00 Europe/London

Room G59 (Diamond House)

Welcome to the joint MXCuBE-ISPyB meeting co-organised by Diamond Light Source (DLS) and Global Phasing Ltd and hosted at Diamond House (DLS). The MXCuBE-ISPyB meeting (November 17^th-19^th) will comprise brief facility reports, scientific presentations and group discussions. Remote participation is possible via Zoom.

Monday 17 November

Diamond beamline tour for early arrivals

Arrival and Registration (with refreshments)

Lunch

ISPyB: Status Reports

1 Welcome

2 ALBA (Barcelona, Spain)

Speaker: Marc Armenter Hierro (ALBA)

ALBA_MarcArmentierHierro_Ispyb_Meeting_Diamond_2025.pptx

3 MAX IV (Lund, Sweden)

Speaker: Alberto Nardella (MAXIV)

MAXIV_AlbertoNardella_ISPyB_Meeting_Diamond_2025.pdf

4 DESY (Hamburg, Germany)

Speaker: Johanna Hakanpaeae (DESY)

DESY_JohannaHakanpaa_ISPyB_2025_2.pdf

5 Oulu University (Finland)

Speaker: Ed Daniel (Oulu University)

Oulu_EdDaniel_ISPyB.pptx

6 SOLEIL (Paris, France)

Speaker: Mohsen Dahesh (Soleil)

SOLEIL_MohsenDahesh_Status-report-MXCuBE-ISPyB Diamond-Nov-2025_bis.pdf

7 ELETTRA (Trieste, Italy)

Speaker: Alessandro Olivo (Elettra)

Elettra_AlessandroOlivo_2025_11_17_ISPyB_status_report.pdf

8 DLS (Oxford, UK)

Speaker: James Hall (DLS)

DLS_JamesHall_Update_to_ISPyB_Meeting_at_Diamond.pptx

9 Global Phasing (Cambridge, UK)

Speaker: Rasmus Fogh (Global Phasing Ltd.)

GPhL_RasmusFogh_ISPyB_status_final.pdf

10 ESRF (Grenoble, France)

Speaker: Alex de Maria (ESRF)

ESRF_AlexDeMaria_ISPyB_MXCube Nov 2025 DLS ESRF-1.pdf

15:20 Coffee break

ISPyB: Scientific Presentations

11 Crystal Size Matters: Triaging Approaches for Micro- and Nano-crystals at Diamond

Speaker: Anna Warren (DLS)

DLS_AnnaWarren_Crystal Size Matters: Triaging Approaches for Micro- and Nano-crystals at Diamond.pptx

12 Electron diffraction: why it is difficult and why it is (hopefully) worth it

Speaker: David Owen (DLS)

DLS_DavidOwen_Electron diffraction: why it is difficult and why it is (hopefully) worth it.pptx

Open Discussion: Introduction to committees discussion - Joint Session

Parallel Sessions ISPyB: Developers

Parallel Sessions ISPyB: Steering Comittee

Reports of StC+Dev Parallel Discussions: ISPyB

Steering_Committee_Report.txt

18:30 Dinner

Tuesday 18 November

Scientific Session - Addressing the Fragmentation of Communication between Synchrotrons, Developers and Industrial MX Users: Part-1 (Interoperability in Synchrotron Logistics)

13 Rationale and Purpose of Day 2

Addressing the Fragmentation of Communication between Synchrotrons, Developers and Industrial MX Users.

Speaker: Gerard Bricogne (Global Phasing Ltd.)

GPhL_GerardBricogne Rationale and Purpose of Day 2.pptx

14 A tale of six synchrotrons

Speaker: May Sharpe (FFCS, Paul Scherrer Institute)

PSI_MaySharpe_MXCuBE_ISPyB_November_2025.pptx

15 A close-up view of synchrotron diversity from a user’s viewpoint

Speaker: Dennis Stegmann (FFCS, Paul Scherrer Institute)

PSI_DennisStegmann_MXCube_meeting_DLS_2025_fin.pptx

16 Synchrotron logistics with MXLIMS, starting with standardised experiment submission and result retrieval

Speaker: Rasmus Fogh (Global Phasing Ltd.)

GPhL_RasmusFogh_MXLIMS_Diamond_2025_final.pdf

17 OAuth2 and authentication standardisation across facilities

Speaker: Guilherme Francisco de Freitas (Diamond Light Source)

DLS_GuilhermeFranciscoDeFreitas OAuth2 and authentication standardisation across facilities.pptx

10:00 Coffee break

Scientific Session - Addressing the Fragmentation of Communication between Synchrotrons, Developers and Industrial MX Users: Part-2 (Interoperability in Synchrotron Logistics)

18 Overcoming the Challenges of Scaling MX in the Cloud

Speaker: Oleg Mikhailovskii (CryoCloud B.V.)

CryoCloud_OlegMikhailovskii 20251118 MX Pipeline-2.pptx

19 Complexity of multi-synchrotron operations for a Pharma company

Speaker: Patrik Johansson (AstraZeneca Sweden)

AZ_PatrikJohansson_ISPYB_MXCUBE_meeting_2025.pdf

20 Complexity of multi-synchrotron operations for a small CRO

Speaker: Christian Becke (MoloX)

MOLOX_Christian_Becke_20251118_ISPyB_meeting_final.pptx

21 Standardising (auto-)processing and access to its results while avoiding Procrustean beds

Speaker: Clemens Vonrhein (Global Phasing Ltd.)

GPhL_ClemensVonrhein_Standardising-auto-processing-and-access-to-its-results-while-avoiding-Procrustean-beds.pdf

Open Discussion: Prospects for achieving interoperability between synchrotrons

22 Prospects for achieving interoperability between synchrotrons

12:00 Lunch

Scientific Session - Addressing the Fragmentation of Communication between Synchrotrons, Developers and Industrial MX Users: Part-3 (Data Quality Assurance Measures)

23 The XDS crisis: a spontaneously-arising stress test of our coordinated response capabilities

Speaker: Gerard Bricogne (Global Phasing Ltd.)

GPhL_GerardBricogne The XDS crisis.pptx

24 Lessons learned from the assessment of successive problematic XDS versions

Speaker: Clemens Vonrhein (Global Phasing Ltd.)

GPhL_ClemensVonrhein_XDS-Saga-Lessons-Learned.pdf

25 Reproducibility checks in the Dectris Cloud

Speaker: Camilla Buhl Larsen (Dectris Ltd.)

Dectris_CamillaBuhlLarsen_Scientific_reproducibility_pipelines.pptx

26 The Industrial Access Beamline Validation Proposal

Speaker: Gerard Bricogne (Global Phasing Ltd.)

The Industrial Access Beamline Validation Proposal.pptx

Open Discussion

15:00 Discussion on QA, including ...

• visibility of beamline validation
• collective vigilance
• rapid reaction
• digging deeper into Data Quality Metrics

15:30 Coffee break & Group Picture

Scientific Session - Addressing the Fragmentation of Communication between Synchrotrons, Developers and Industrial MX Users: Part-4 (Direct Metadata Capture at Synchrotrons for AI/ML-related depositions)

27 The DRI Project and forthcoming activities to support metadata-rich depositions

Speaker: Genevieve Evans (PDBe)

PDBe_GenevieveEvans_2025_MXCUBE_ISPyB_GLE-DH.pdf

28 Homebrewed Crystallographic Data Management in an Academic Setting

Speaker: Marko Hyvönen (Cambridge University)

UCambridge_MarkoHyvonen_MXcube_meeting_20251119.pptx

29 Metadata quality assurance in (group) depositions

Speaker: Clemens Vonrhein (Global Phasing Ltd.)

GPhL_ClemensVonrhein_Metadata-quality-assurance-in-group-depositions.pdf

Open Discussion: The Art of the Possible - Pledges and Priorities.

Conference Dinner

30 Drinks

31 Dinner

Wednesday 19 November

MXCuBE: Status Reports - Part 1

32 Beamline remote access at the Australian Synchrotron

Speaker: Andreas Moll (ANSTO (Australian Synchrotron))

ANSTO_Andreas_Moll_MXCuBE_ISPyB_Nov_2025_ANSTO.pdf

33 Expression of interest in the MXCuBE Collaboration

Speaker: Mi-Jeong Kwak (Pohang Accelerator Laboratory (PAL))

4GSR_Mi_Jeong_Kwak_20251119_MXCuBE_meeting.pdf

34 NFPSS (Shanghai, China)

Speaker: Kangwen Bao (NFPSS/SSRF)

SSRF_Kangwen_Bao_StatusofNCPSSMXbeamlinesatSSRF.pdf

35 ALBA (Barcelona, Spain)

Speaker: José Centeno Gabadinho (ALBA)

ALBA_JoseCentenoGabadinho_MXCuBE_SiteReport_ALBA_Nov2025.pdf

36 HZB-BESSY (Berlin, Germany)

Speaker: Michael Hellmig (HZB)

37 DESY (Hamburg, Germany)

Speaker: Andrey Gruzinov (DESY)

DESY_Andrey_Gruzinov_MXCuBE_DESY_Report_Nov2025.pdf

38 ELETTRA (Trieste, Italy)

Speaker: Alessandro Olivo (Elettra)

Elettra_AlessandroOlivo_2025_11_19_MXCuBE_status_report.pdf

39 EMBL (Hamburg, Germany)

Speaker: Gleb Bourenkov (EMBL-HH)

40 MAX IV (Lund, Sweden)

Speaker: Ezequiel Panepucci (MAXIV)

MAXIV_EzequielPanepucci_MXCuBE_Status_report.pdf

10:04 Coffee Break

MXCuBE: Status Reports - Part 2

41 MANACA @ LNLS (Campinas, Brazil)

Speaker: Pedro Benetton (LNLS)

LNLS_PedroBenetton_MXCuBE_Presentation_2S2025.pdf

42 ESS (Lund, Sweden)

Speaker: Lais Pessine Do Carmo (ESS)

ESS_LaisPessineDoCarmo_SiteReport_MXCuBE_ESS__Diamond_nov25.pdf

43 LS-CAT @ APS (Chicago, United States)

Speaker: Joe Brunzelle (LS-CAT)

LSACT_JoeBrunzelle_MXCuBE_LSCAT_Mtg_20251119.pptx

44 SOLARIS @ NSRC (Krakow, Poland)

Speaker: Michal Gucwa (SOLARIS)

SOLARIS_MichalGucwa_ARYA_MXCuBE_Meeting_Nov_2025_.pptx

45 SOLEIL (Paris, France)

Speaker: Martin Savko (Soleil)

SOLEIL_MartinSavko_Status-report-MXCuBE-ISPyB_Diamond-Nov-2025.pptx

46 ESRF (Grenoble, France)

Speaker: Marcus Oskarsson (ESRF)

ESRF_MarcusOskarsson_status_report_mxcube_november_2025.pptx.pdf

47 Global Phasing, UK

Speaker: Rasmus Fogh (Global Phasing Ltd.)

GPhL_RasmusFogh_MXCuBE_status_final.pdf

MXCuBE: Scientific Presentations

48 Report from the Automation Working Group

Speaker: Didier Nurizzo (ESRF)

ESRF_DNurizzo_Automation_WG_Status.pptx

Open Discussion: MXCuBE Developments

12:30 Lunch

Parallel Sessions MXCuBE: Developers

MXCuBE_Diamond2025_developers.docx

Parallel Sessions MXCuBE: Steering Committee

MXCuBE_Diamond2025_steering.docx

Reports of StC+Dev Parallel Discussions: MXCuBE

15:00 Coffee break & Early Leave